Protein Modification Reagents
Medchemexpress LLC DiSulfo-Cy5 alkyne | 1617497-19-4 | C35H40N3NaO7S2 | 1 MG
DiSulfo-Cy5 alkyne is a fluorescent dye that can be used as a click chemistry reagent.
- Fluorescent dye
- Click chemistry reagent
![eMolecules DOPE-PEG-Fluor 488, MW 2,000 | Broadpharm |1369.560 | C65H94N4NaO20PS2 | 98.000 | [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)OCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=[NH2+])ccc12)S([O-])(=O)=O)S(O)(=O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC | 1mg | 798870839](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502508684.JPG-250.jpg)
eMolecules DOPE-PEG-Fluor 488, MW 2,000 | Broadpharm |1369.560 | C65H94N4NaO20PS2 | 98.000 | [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)OCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=[NH2+])ccc12)S([O-])(=O)=O)S(O)(=O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC | 1mg | 798870839
DOPE-PEG-Fluor 488, MW 2,000 | Broadpharm |1369.560 | C65H94N4NaO20PS2 | 98.000 | [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCCNC(=O)OCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=[NH2+])ccc12)S([O-])(=O)=O)S(O)(=O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC | 1mg | 798870839
Medchemexpress LLC PROTAC STING degrader-3 | 3109967-69-0 | 98.0% | 752.73 | 1 MG
PROTAC STING degrader-3 is a STING PROTAC degrader that induces STING degradation via the ubiquitin-proteoteasome pathway. It exerts anti-inflammatory effects by inhibiting STING/TBK1/NF-κB signaling and has renal protective effects, making it useful in the study of acute kidney injury (AKI).
- STING ligand
- Cereblon ligand
- Linker
Medchemexpress LLC DSPE-PEG3-azide | 97.0% | 977.30 | 100 MG
DSPE-PEG3-azide (DSPE-PEG3-N3) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery. It is a click chemistry reagent that contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Can be used to form micelles as nanoparticles for drug delivery.
- Contains an azide group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
Vector Laboratories VECTOR LABORATORIES LLC TCO-PEG3-Maleimide, MW 523.62, Purity >95%
TCO-PEG3-Maleimide enables simple and efficient incorporation of TCO moiety onto antibodies, cysteine-containing peptides and other thiol-containing molecules. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form stable thioether bonds. The hydrophilic polyethylene glycol (PEG) spacer arm improves solubility in aqueous buffers.
- CAS number: 1609659-01-9
- Molecular weight: 523.62
- Molecular formula: C26H41N3O8
- Appearance: Colorless to slightly yellow oil
- Purity: >95% (HPLC)
- Solubility: DMSO, DMF, DCM, THF, Chloroform
- Storage instructions: −50°C to −85°C
- Shipping conditions: Dry ice
- For research use only.
Broadpharm Bromo-PEG3-CH2CO2tBu | 2100306-71-4 | MFCD30723231 | 500mg
Bromo-PEG3-CH2CO2tBu | Putity: 98% | MW: 327.2 | 2100306-71-4 | MFCD30723231 | 500mg
STA Pharmaceutical Fmoc-NH-PEG6-CH2CH2COOH | 100 g | CAS 882847-34-9 | MDL MFCD06656474
Fmoc-NH-PEG6-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 882847-34-9
- MDL: MFCD06656474
- InChIKey: HEGZERUHBVYZPH-UHFFFAOYSA-N
- Molecular Weight: 575.655
- Molecular Formula: C30H41NO10
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Vh285-peg4-c4-cl (haloprotac 3) | 1799506-07-2 | 96.49% | 799.42 | 100 MG
VH285-PEG4-C4-Cl (HaloPROTAC 3) is a conjugate of ligands for E3 and a 16-atom-length linker. The connector of the linker is a Halogen group. It incorporates the VH285 based VHL ligand and an alkyl/ether-based linker. It is a highly potent and efficacious degrader of GFP-HaloTag7, binding to VHL.
- Highly potent and efficacious degrader of GFP-HaloTag7 with a DC50 of 19 nM.
- Able to induce 90% degradation of GFP-Halotag at 625 nM.
- Binds to VHL with an IC50 of 0.54 μM.
- Treatment with 500 nM of the product is able to induce nearly complete knockdown of both HaloTag7-ERK1 and HaloTag7-MEK1.
Medchemexpress LLC Dspe-peg-alkyne | 85.0% | 2000 | 25 MG
DSPE-PEG-alkyne (MW 2000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. It can be used in drug delivery research.
- Peg lipid
- Improves delivery efficiency
- Enhances tissue specificity for poorly soluble drugs
- Suitable for drug delivery research
Medchemexpress LLC Cc-885-ch2-peg1-nh-ch3 | 2722698-03-3 | 99.2% | 528.00 | C26H30ClN5O5 | 25 MG
CC-885-CH2-PEG1-NH-CH3 is a small-molecule neoDegrader used as the cytotoxic payload in antibody-based neoDegrader conjugates (AnDCs) to enable targeted protein degradation via the E3 ubiquitin ligase pathway. It is supplied for laboratory research use.
- Used in synthesis of antibody neoDegrader conjugates.
- Enables targeted protein degradation via the E3 ubiquitin ligase pathway.
- Molecular formula C26H30ClN5O5; molecular weight 528.00 g/mol.
- Purity 99.2% and solid, white to off-white appearance.
- Storage: 4°C (sealed); in solvent, -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC (S,R,S)-AHPC-PEG2-N3 | 2010159-45-0 | 99.9% | 601.72 g/mol | C28H39N7O6S | 5 MG
(S,R,S)-AHPC-PEG2-N3 is an E3 ligase ligand-linker conjugate bearing a terminal azide for click chemistry, used as a building block in PROTAC synthesis and bioconjugation.
- Terminal azide enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition.
- Two-unit PEG linker provides solubility and spacer functionality.
- Designed for conjugation to alkyne, DBCO, or BCN functional partners.
- Supplied in small-quantity formats for research and synthesis workflows.
- Molecular weight 601.72 g/mol; molecular formula C28H39N7O6S.
eMolecules 123502-57-8 | Bis-PEG11-NHS ester | Broadpharm | MFCD30527397 | 796.817 | C34H56N2O19 | 95.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 500mg | 340377030
Bis-PEG11-NHS ester | Broadpharm | 123502-57-8 | MFCD30527397 | 796.817 | C34H56N2O19 | 95.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 500mg | 340377030
Medchemexpress LLC Mal-PEG8-Phe-Lys-PAB-Exatecan TFA | 98.7% | 1548.58 | 5 MG
Mal-PEG8-Phe-Lys-PAB-Exatecan TFA is an agent-linker conjugate for antibody-drug conjugates (ADC), composed of the degradable linker Mal-PEG8-Phe-Lys-PAB and the toxin molecule Exatecan. This agent is intended for research use only.
- Composed of degradable linker Mal-PEG8-Phe-Lys-PAB
- Contains toxin molecule Exatecan
- Carries a highly potent small-molecule toxin
- Targets specific antigens of tumor cell surfaces with high binding affinity
- Internalized into tumor cells and digested in lysosome to release antitumor toxin